{"id":54488,"date":"2022-11-16T08:51:49","date_gmt":"2022-11-16T12:51:49","guid":{"rendered":"http:\/\/www.ing.una.py\/?p=54488"},"modified":"2024-12-05T12:56:05","modified_gmt":"2024-12-05T15:56:05","slug":"investigador-de-la-fiuna-expone-trabajo-cientifico-en-el-4to-congreso-mundial-de-electroporacion-celular-en-copenhague-dinamarca","status":"publish","type":"post","link":"https:\/\/www.ing.una.py\/FIUNA3\/?p=54488","title":{"rendered":"Investigador de la FIUNA expone trabajo cient\u00edfico en el 4to Congreso Mundial de Electroporaci\u00f3n Celular en Copenhague, Dinamarca"},"content":{"rendered":"<p><![CDATA[El trabajo de investigaci\u00f3n titulado <em>\u201cExperimental and theoretical Brownian Dynamics analysis of ion transport during cellular electroporation of E. coli bacteria\u201d<\/em> fue presentado por el Docente Investigador <strong>Juan A. Gonz\u00e1lez Cuevas<\/strong>, vinculado al <strong>Laboratorio de Mec\u00e1nica y Energ\u00eda<\/strong> de la<strong>\u00a0Facultad de Ingenier\u00eda de la Universidad Nacional de Asunci\u00f3n (FIUNA)<\/strong>, en el<strong> <em>4th World Congress on Electroporation Pulsed Electric Fields in Biology, Medicine, Food and Environmental Technologies <\/em><\/strong><a href=\"https:\/\/wc2022.electroporation.net\/\"><strong>https:\/\/wc2022.electroporation.net\/<\/strong><\/a> que se llev\u00f3 a cabo los d\u00edas 9 al 13 de octubre del corriente en Copenhague, Dinamarca con la participaci\u00f3n de m\u00e1s de 400 investigadores de 31 pa\u00edses.<!--more-->\n\nEl trabajo consiste en la simulaci\u00f3n tridimensional del transporte de iones de calcio, magnesio, sodio, potasio y cloro a trav\u00e9s de las membranas interna y externa de la bacteria Escherichia coli durante la permeabilizaci\u00f3n por electroporaci\u00f3n, usando un modelo de din\u00e1mica Browniana que es principalmente determin\u00edstico siguiendo la mec\u00e1nica Newtoniana, considerando estoc\u00e1sticamente las colisiones el\u00e1sticas de los iones con el agua. La conductividad, coeficiente de difusi\u00f3n, movilidad y tiempo de traslaci\u00f3n de los iones son estimados con el modelo y validados con experimentos realizados en el <strong>Instituto Oncol\u00f3gico<\/strong> <b>Gustave Roussy en Villejuif-Par\u00eds, Francia<\/b>, contribuyendo de esta manera al dise\u00f1o de las formas de las ondas de pulsos electromagn\u00e9ticos aplicados para maximizar la entrada de ADN, medicamentos y material gen\u00e9tico en las c\u00e9lulas. Entre las principales aplicaciones m\u00e9dicas de la electroporaci\u00f3n se encuentran el tratamiento de diferentes tipos de tumores cancer\u00edgenos y la ablaci\u00f3n cardiaca.\n\n[caption id=\"attachment_54489\" align=\"alignleft\" width=\"217\"]<img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"54489\" data-permalink=\"https:\/\/www.ing.una.py\/FIUNA3\/?attachment_id=54489\" data-orig-file=\"https:\/\/www.ing.una.py\/FIUNA3\/wp-content\/uploads\/2022\/11\/Membrana_celular.jpg\" data-orig-size=\"217,233\" data-comments-opened=\"1\" data-image-title=\"Membrana_celular\" data-image-description=\"&lt;p&gt;&lt;![CDATA[]]&gt;    \t&lt;\/p&gt;\n\" data-image-caption=\"&lt;p&gt;Permeabilizaci\u00f3n de la membrana celular por electroporaci\u00f3n&lt;\/p&gt;\n\" data-large-file=\"https:\/\/www.ing.una.py\/FIUNA3\/wp-content\/uploads\/2022\/11\/Membrana_celular.jpg\" class=\"wp-image-54489 size-full\" src=\"http:\/\/www.ing.una.py\/FIUNA3\/wp-content\/uploads\/2022\/11\/Membrana_celular.jpg\" alt=\"\" width=\"217\" height=\"233\" \/> Permeabilizaci\u00f3n de la membrana celular por electroporaci\u00f3n[\/caption]\n\nEl modelo fue ejecutado con aceleraci\u00f3n de intercambio de mensajes (MPI) en el Centro de C\u00f3mputos de Alto Desempe\u00f1o ubicado en CITEC, Isla Bogado, Luque. La investigaci\u00f3n fue financiada en su etapa inicial por el<strong>\u00a0Consejo Nacional de Ciencia y Tecnolog\u00eda (CONACYT),<\/strong>\u00a0en el marco del <strong>proyecto 14-INV-289<\/strong> con un aporte incremental proporcionado por la FIUNA. Adem\u00e1s se organiz\u00f3 el evento cient\u00edfico \u201c<strong>Primer Simposio de Electroporaci\u00f3n Celular del Paraguay\u201d<\/strong>\n\n<strong>(<a href=\"http:\/\/www.ing.una.py\/?page_id=41931\">CONACYT VEVE19-185<\/a><\/strong>),pospuesto debido a la pandemia.\n\n&nbsp;\n\n&nbsp;\n\n&nbsp;\n\n[gallery type=\"rectangular\" columns=\"2\" size=\"medium\" link=\"file\" ids=\"54492,54491\"]]]>    \t<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u201cExperimental and theoretical Brownian Dynamics analysis of ion transport during cellular electroporation of E. coli bacteria\u201d fue presentado por el Docente Investigador Juan A. Gonz\u00e1lez Cuevas, vinculado al Laboratorio de Mec\u00e1nica y Energ\u00eda de la\u00a0Facultad de Ingenier\u00eda de la Universidad Nacional de Asunci\u00f3n (FIUNA), en el 4th World Congress on Electroporation Pulsed Electric Fields in Biology, Medicine, Food and Environmental Technologies https:\/\/wc2022.electroporation.net\/ que se llev\u00f3 a cabo los d\u00edas 9 al 13 de octubre del corriente en Copenhague, Dinamarca con la participaci\u00f3n de m\u00e1s de 400 investigadores de 31 pa\u00edses.<\/p>\n","protected":false},"author":1,"featured_media":54490,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"page_builder":"","_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[226,75,349],"tags":[384,347,205],"class_list":["post-54488","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-investigaciones","category-noticias","category-publicacion-de-investigacion","tag-conacyt","tag-direccion-de-investigacion","tag-laboratorio-de-mecanica-y-energia"],"jetpack_publicize_connections":[],"jetpack_shortlink":"https:\/\/wp.me\/pc8Odv-eaQ","jetpack_likes_enabled":true,"jetpack_sharing_enabled":true,"jetpack-related-posts":[{"id":58108,"url":"https:\/\/www.ing.una.py\/FIUNA3\/?p=58108","url_meta":{"origin":54488,"position":0},"title":"Investigadores de la FIUNA publicaron trabajo cient\u00edfico en reconocida revista  internacional y expusieron en congreso mundial","author":"Admin","date":"15\/09\/2023","format":false,"excerpt":"Investigadores de la Facultad de Ingenier\u00eda de la Universidad Nacional de Asunci\u00f3n (FIUNA) publicaron el art\u00edculo cient\u00edfico denominado \u201cExperimental and theoretical Brownian dynamics analysis of ion transport during cellular electroporation of E. coli bacteria\u201d en la revista internacional interdisciplinaria de alto impacto Annals of Biomedical Engineering de la prestigiosa editorial\u2026","rel":"","context":"En \u00abInvestigaci\u00f3n FIUNA\u00bb","block_context":{"text":"Investigaci\u00f3n 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4x"},"classes":[]},{"id":55046,"url":"https:\/\/www.ing.una.py\/FIUNA3\/?p=55046","url_meta":{"origin":54488,"position":2},"title":"Investigadores de la FIUNA publican art\u00edculo cient\u00edfico en referente revista internacional de la IEEE","author":"Admin","date":"09\/08\/2021","format":false,"excerpt":"Investigadores adscritos al Laboratorio de Sistemas de Potencia y Control (LSPyC), perteneciente al Departamento de Ingenier\u00eda Electr\u00f3nica y Mecatr\u00f3nica, de Facultad de Ingenier\u00eda de la Universidad Nacional de Asunci\u00f3n (FIUNA) han publicado recientemente el art\u00edculo\u00a0 titulado \u201cPareto Optimal Weighting Factor Design of Predictive Current Controller of a Six-Phase Induction Machine\u2026","rel":"","context":"En \u00abInvestigaci\u00f3n FIUNA\u00bb","block_context":{"text":"Investigaci\u00f3n 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Volume 20, Issue 2. Ver. III (February. 2018), PP 33-40 DOI: 10.9790\/487X-2002033340, public\u00f3 el art\u00edculo titulado \u201cFinancial Feasibility for the Sale of Certificates of Reduced Emissions (CER's) In Carbon Markets, Using The Analytical Hierarchical Process (AHP). Wind Power Energy\u2026","rel":"","context":"En \u00abInvestigaci\u00f3n FIUNA\u00bb","block_context":{"text":"Investigaci\u00f3n FIUNA","link":"https:\/\/www.ing.una.py\/FIUNA3\/?cat=226"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.ing.una.py\/FIUNA3\/wp-content\/uploads\/2018\/02\/publicacion-Mitjans-Pulfer.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.ing.una.py\/FIUNA3\/wp-content\/uploads\/2018\/02\/publicacion-Mitjans-Pulfer.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/www.ing.una.py\/FIUNA3\/wp-content\/uploads\/2018\/02\/publicacion-Mitjans-Pulfer.jpg?resize=525%2C300&ssl=1 1.5x"},"classes":[]},{"id":29866,"url":"https:\/\/www.ing.una.py\/FIUNA3\/?p=29866","url_meta":{"origin":54488,"position":4},"title":"IOSR Journal of Electrical and Electronics Engineering (IOSR-JEEE) publica trabajo de docentes investigadores de la FIUNA","author":"Admin","date":"02\/04\/2018","format":false,"excerpt":"IOSR Journal of Electrical and Electronics Engineering por sus siglas (IOSR-JEEE) e-ISSN: 2278-1676, p-ISSN: 2320-3331, DOI: 10.9790\/1676-130104738, Factor de Impacto 3,26; public\u00f3 el art\u00edculo titulado \u201cEnergy Efficiency Assessment of Four Designs of Vertical Axis And Drag Differential Wind Turbines\u201d. Dicha investigaci\u00f3n fue llevada a cabo en el Laboratorio de Mec\u00e1nica\u2026","rel":"","context":"En \u00abInvestigaci\u00f3n FIUNA\u00bb","block_context":{"text":"Investigaci\u00f3n FIUNA","link":"https:\/\/www.ing.una.py\/FIUNA3\/?cat=226"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.ing.una.py\/FIUNA3\/wp-content\/uploads\/2018\/04\/Captura.jpg?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":51444,"url":"https:\/\/www.ing.una.py\/FIUNA3\/?p=51444","url_meta":{"origin":54488,"position":5},"title":"Docente Investigador de la FIUNA publica un art\u00edculo en una revista de alto impacto","author":"Admin","date":"11\/05\/2022","format":false,"excerpt":"El Prof. MSc. 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